Scientific Image Gallery
Granulocytes with typical reddish granulation of a patient treated with granulocyte growth factor (G-CSF).
<p>Granulocytes with typical reddish granulation of a patient treated with granulocyte growth factor (G-CSF).</p>
Cell description:
Size: larger than normal lymphocytes
Nucleus: round, oval, dumbbell-shaped or bilobed with little chromatin condensation and sometimes indistinct nucleolus
Cytoplasm: abundant weakly basophilic with irregular “hairy” margins
<p>Cell description: </p> <p>Size: larger than normal lymphocytes </p> <p>Nucleus: round, oval, dumbbell-shaped or bilobed with little chromatin condensation and sometimes indistinct nucleolus </p> <p>Cytoplasm: abundant weakly basophilic with irregular “hairy” margins</p>
Hairy cell from a hairy cell leukaemia. Typical are the monocytic type nuclei with loose chromatin, and the grey-blue, heterogeneous cytoplasm. The hairy protrusions may be missing in some cases.
<p>Hairy cell from a hairy cell leukaemia. Typical are the monocytic type nuclei with loose chromatin, and the grey-blue, heterogeneous cytoplasm. The hairy protrusions may be missing in some cases.</p>
Peripheral blood (May-Grünwald-Giemsa stain) of a patient with hairy cell leukaemia. A typical hairy cell (->) can easily be distinguished from a normal lymphocyte (lower right).
<p>Peripheral blood (May-Grünwald-Giemsa stain) of a patient with hairy cell leukaemia. A typical hairy cell (->) can easily be distinguished from a normal lymphocyte (lower right).</p>
Hairy cell leukaemia-variant (HCL-V).
<p>Hairy cell leukaemia-variant (HCL-V).</p>
This 'hairy' lymphocyte comes from a person suffering from an active infection (without any malignant disease). The granula identify it as a T or an NK cell.
<p>This 'hairy' lymphocyte comes from a person suffering from an active infection (without any malignant disease). The granula identify it as a T or an NK cell.</p>
Reticulocyte staining. Characteristic HbH cell in a case of α-thalassaemia. Today, blood films are no longer investigated for HbH cells. Instead,
α-thalassaemias are diagnosed by molecular genetic tests.
<p>Reticulocyte staining. Characteristic HbH cell in a case of α-thalassaemia. Today, blood films are no longer investigated for HbH cells. Instead, </p> <p>α-thalassaemias are diagnosed by molecular genetic tests.</p>
A remarkably high and conspicuous number of megakaryocytes (->) is visible in the bone marrow histology (Giemsa stain) of a patient with CML.
<p>A remarkably high and conspicuous number of megakaryocytes (->) is visible in the bone marrow histology (Giemsa stain) of a patient with CML. </p>
Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes.
<p>Bone marrow histology (Giemsa stain) showing two Hodgkin cells (H). These giant cells have an oval, non-lobulated nucleus and at least one nucleolus. Reed-Sternberg cells (RS) have a lobulated nucleus with several nucleoli. Both cell types are characteristic of Hodgkin's disease and express the same surface marker CD30, which is otherwise found on activated lymphocytes. </p>